Thornton Melon (Rodney Dangerfield) is concerned that his son Jason (Keith Gordon) is unsure whether to go to college, so the uneducated self-made millionaire encourages him by signing up as a student as well. As Jason tries to establish himself among his peers and make the diving team, Thornton falls for a pretty professor (Sally Kellerman) and gets others do his schoolwork for him. When the suspicious dean (Paxton Whitehead) finds out, Thornton needs to show he can get by on his own.
The film follows the misadventures of Jack Skellington, Halloweentown’s beloved pumpkin king, who has become bored with the same annual routine of frightening people in the “real world.” When Jack accidentally stumbles on Christmastown, all bright colors and warm spirits, he gets a new lease on life. He plots to bring Christmas under his control by kidnapping Santa Claus and taking over the role. But Jack soon discovers even the best-laid plans of mice and skeleton men can go seriously awry.
Ash is transported back to medieval days, where he is captured by the dreaded Lord Arthur. Aided by the deadly chainsaw that has become his only friend, Ash is sent on a perilous mission to recover the Book of the Dead, a powerful tome that gives its owner the power to summon an army of ghouls.
Pee-wee Herman (Paul Reubens), an eccentric child-like man, loves his red bicycle and will not sell it to his envious neighbor, Francis (Mark Holton). While Pee-wee visits his friend Dottie (Elizabeth Daily), the bike is stolen. Thinking his bike is at the Alamo, Pee-wee sets off on a trip, where he meets many remarkable people, including waitress Simone (Diane Salinger) and a motorcycle gang. Eventually, Pee-wee discovers that his bike is being used in a movie and tries to recover it.
A scientist (Vincent Price) builds an animated human being — the gentle Edward (Johnny Depp). The scientist dies before he can finish assembling Edward, though, leaving the young man with a freakish appearance accentuated by the scissor blades he has instead of hands. Loving suburban saleswoman Peg (Dianne Wiest) discovers Edward and takes him home, where he falls for Peg’s teen daughter (Winona Ryder). However, despite his kindness and artistic talent, Edward’s hands make him an outcast.
After Barbara (Geena Davis) and Adam Maitland (Alec Baldwin) die in a car accident, they find themselves stuck haunting their country residence, unable to leave the house. When the unbearable Deetzes (Catherine O’Hara, Jeffrey Jones) and teen daughter Lydia (Winona Ryder) buy the home, the Maitlands attempt to scare them away without success. Their efforts attract Beetlejuice (Michael Keaton), a rambunctious spirit whose “help” quickly becomes dangerous for the Maitlands and innocent Lydia.