Jack Spade (Keenen Ivory Wayans) comes home to the ghetto and finds his brother dead from a gold chain overdose. With the help of his hero, John Slade (Bernie Casey), and a team of washed-up crime fighters, Spade declares vengeance on Mr. Big (John Vernon), the white crime leader responsible for selling gold chains on the streets. But Spade realizes that he must take matters into his own hands to finish the job in this zany spoof of 1970s blaxploitation films.
After an airport mishap leaves businessman Marshall Seymour (Judge Reinhold) in possession of a mysterious skull following a trip to the South Pacific, he unwittingly falls victim to its magical powers when he and his son Charlie (Fred Savage) swap bodies. Unable to switch back, each must lead the other’s life while trying to figure out the cause of the sudden change — all the while avoiding a pair of smugglers intent on getting their hands on the apparently valuable skull.
Frank Drebin (Leslie Nielsen), a rather clueless police detective, tries to foil a plot to turn innocent people into assassins through mind control. After his partner, Norberg (O.J. Simpson), is shot, Frank sets out to find the culprit, leading him to business tycoon Vincent Ludwig (Ricardo Montalban). However, Frank has no evidence until he meets Jane Spencer (Priscilla Presley), Ludwig’s assistant. She knows nothing about Ludwig’s devious plans, but falls for Frank and agrees to help him.
Prior to his death on the crucifix, Jesus Christ (Jürgen Prochnow) was offered a drink of water, a kind act turned away by a Roman soldier. These events play a profound role in occurrences during modern times, which some construe as signs of Christ’s return and the apocalypse. While Abby Quinn (Demi Moore) believes the end is coming and that her unborn child may be in danger as a result, Father Lucci (Peter Friedman), a Vatican agent, is doubtful no matter what evidence she presents.
It’s vacation time for outdoorsy Chicago man Chet Ripley (John Candy), along with his wife, Connie (Stephanie Faracy), and their two kids, Buck (Chris Young) and Ben (Ian Giatti). But a serene weekend of fishing at a Wisconsin lakeside cabin gets crashed by Connie’s obnoxious brother-in-law, Roman Craig (Dan Aykroyd), his wife, Kate (Annette Bening), and the couple’s two daughters. As the excursion wears on, the Ripleys find themselves at odds with the stuffy Craig family.
In a seaside California town, best friends Mac (Mel Gibson) and Nick (Kurt Russell) are on opposite sides of the law. Mac is a former drug dealer trying to clean up his act, while Nick is a high-profile detective trying to take down a Mexican drug lord named Carlos (Raul Julia). Soon Nick’s loyalties are put to the test when he begins an affair with restaurateur Jo Ann (Michelle Pfeiffer) — a love interest of Mac’s — unwittingly leading his friend into a police-orchestrated trap.
The apparently comatose Michael Myers (George P. Wilbur) is being transferred from one hospital to another, but he wakes up when the ambulance crew talk about his surviving niece, Jamie (Danielle Harris). After slaughtering his attendants, Myers sets out to find his one living relative who is, fortunately, being cared for by a kind and resourceful foster sister named Rachel (Ellie Cornell). Meanwhile, the ever-cautious Dr. Loomis (Donald Pleasence) remains on the killer’s path.
John Tunstall (Terence Stamp), a distinguished British gentleman, employs downtrodden youths to tend his herd on the New Mexican frontier. When Tunstall is gunned down by the crooked Lawrence G. Murphy (Jack Palance), a ragtag group of cowhands — including Doc Scurlock (Kiefer Sutherland), Richard Brewer (Charlie Sheen) and young William “Billy the Kid” Bonney (Emilio Estevez) — ride forth in search of bloody vengeance for the death of their beloved mentor.